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Sept 4 (Reuters) – Ionis Pharmaceuticals and partner Novartis’ experimental drug to lower high levels of a cholesterol-carrying particle in heart patients failed in a late-stage trial, the companies said on Friday, sending Ionis’ shares down 12% in aftermarket trading. The drug, pelacarsen, did not meet the main goal of reducing the risk of events such as death from heart disease, heart attack, stroke, or needing an urgent procedure to […]

WASHINGTON (AP) — The widow of an airman killed on a combat mission in the Middle East said it took a viral social media post to get resolution from the Pentagon on issues related to her husband’s benefits and basic pay months after his death. Maj. Alex Klinner, 33, was one of six crew members of a KC-135 refueling aircraft that crashed in western Iraq in March while supporting operations […]

WASHINGTON (AP) — The Supreme Court granted an emergency appeal from Republicans in a dispute over campaign ad prices on Friday, clearing a legal roadblock to political parties getting cheaper TV ad time ahead of the midterm elections. The justices halted for now a lower-court ruling in favor of Democratic candidates who argued that cheaper broadcast ads should be limited to candidates. One justice publicly dissented from the unsigned order. […]

By Field Level Media Sep 04 (Field Level Media) – The Houston Astros’ bullpen took a hit Friday when standout left-hander Steven Okert was placed on the 15-day injured list with a right hamstring strain. The move is retroactive to Sept. 1. Okert last pitched for Houston on Aug. 31, when he allowed one hit and struck out two in a scoreless inning against the Chicago White Sox. Okert is […]

By Shrivathsa Sridhar NEW YORK, Sept 4 (Reuters) – Defending champion Carlos Alcaraz underlined his status as the man to beat at the U.S. Open with a ruthless 6-3 6-4 6-1 victory over China’s Wu Yibing on Friday as he reached the fourth round and continued his bid for a third title at Flushing Meadows. The victory extended Alcaraz’s match-winning streak at the Grand Slams to 17 following his triumph […]

By Jack Queen Sept 4 (Reuters) – The trial of a Massachusetts woman who strangled her three children but argues she is not guilty by reason of insanity ended on Friday with a deadlocked jury. But defendant Lindsay Clancy is still charged with murder and could face a second trial.  Here is a look at what’s next for Clancy, whose televised trial has sparked debate over postpartum mental health treatment in […]

By Field Level Media Sep 04 (Field Level Media) – Clemson became the latest voice to speak out against LSU’s attempt to get additional eligibility for players who spent this offseason on NFL rosters on Friday, according to a Yahoo Sports report. Tight end Dae’Quan Wright and defensive lineman Zxavian Harris — both of whom played for new LSU coach Lane Kiffin last season at Ole Miss and have stated […]

BARI, Italy (AP) — Italy’s Premier Giorgia Meloni celebrated a milestone for her government on Friday, telling a rally of supporters in the southern city of Bari to argue that four years of political stability have strengthened Italy at home and abroad. Her administration has become the longest-serving single government of Italy’s republican era, reaching 1,414 consecutive days in office and surpassing the 1,412-day record set by Silvio Berlusconi ’s […]

Country music icon Dolly Parton was the rare celebrity whose popularity transcended generations and politics. Writing hundreds of songs including classics “Jolene” and “I Will Always Love You,” she was one of music’s most beloved personalities when she died last month. In addition to her musical success, she was also known for her philanthropy and business ventures that included the Dollywood theme park. August also saw the death of actor […]